While the legitimacy of the leaked information can't be officially confirmed until the next edition of OXM hits the streets, there's definitely some food for Mass Effect thought.You will play as Shepard, but for how long is unknown
There is a new species called the Drell and Thane is a new character who is an assassin and may join your party
Planets - There will be a Krogan planet, and Illium, an Asari planet, that is like Coruscant from SW. Also there is "Omega" with is like an anti-Citadel in that it's huge and it's the bottom of the barrel whereas the Citadel is the height of civilization. Also a Cerebus mothership will act as a location of significance.
Story - The ultimate story is still civilization fending off the Reapers, but this chapter will deal with this Cerebus corporation and it's enigmatic leader. There are human civilizations disappearing and it's up to Shepard to investigate, it's termed as a "suicide mission" which may lead to the details of the teaser.
New vehicle that controls better than the Mako…a "new" control scheme.
Totally revamped inventory system
Elevator system revamped where you will get the sense of scope of where you're at and where you're traveling.
No more texture pop in.
Secondary races like Volus and Elcor are much more mobile, giving more depth and makes things more interesting.
Choices are more meaningful and there is a real risk that major support characters (i.e. anyone not Shepard) can and will die.
Also on the story, they're super-hyping the ending, saying that it's much more grand meaningful in ME2.
More weapons, more species, more/new team members.
Returning team members, locations, weapons.

BioWare's collective head explodes over leaked information.


I'm pretty curious to see how the whole "play as Shepard" thing works out. Perhaps it won't be dissimilar to Metal Gear Solid 2: Play as Snake and then experience the crushing realization that you're stuck with Raiden. That was a low blow, by the way.